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Neurology and Neuroscience Research (NNR)

DOI:10.24983/scitemed.nnr
Online ISSN: 2639-8125

Neurology and Neuroscience Research (NNR)

The field of neurology is always full of advances and implementations; there is no edge to the progress it makes. The techniques and practice models are undergoing a rapid transformation. Everyday a new advancement in clinical care and research emerge, which require adaptation and implementation. In such a complex and rapidly transforming area of study, no researcher or clinician becomes too complacent or too relaxed, as it will not take long to fall behind. To provide favorable support in consideration of this scenario, the Neurology and Neuroscience Research journal has been established.

Neurology and Neuroscience Research is put upfront to provide a platform for the free accessibility and publication of research in neurology and the interdisciplinary research areas from round the globe. Neurology and Neuroscience Research is not constrained to a specific disease or a research, but to globalize the works from all the basic areas up to clinical research. The priority of the journal is to accelerate the area of study by providing basic and updated information which would influence the present mode of practice. All the different subsections of neurology are considered but not limited to: neuroanatomy, neurophysiology, neuropsychology, neuroradiology, neurosurgery, neurooncology, neurotoxicology, restorative neurology, and tropical neurology.

Editorial content of the journal features original/research articles, reviews, opinions, commentaries and expert opinions on new developments, clinical trials, clinical protocols, book reviews, perspective, clinical images, etc. All the manuscripts submitted will be subjected for peer-review by the Editors of the respective specialty section.

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Deputy Editor

  • Daniel M. Rosenbaum, MD

    Professor and Chair, Department of Neurology
    Suny Downstate University
    United States
    Prior to his appointment at Downstate, Dr. Rosenbaum was Vice-Chair of the Department of Neurology at Albert Einstein College of Medicine where he served as Professor of Ophthalmology and Neurology and Associate Professor of Neuroscience. He has also held the positions of Site Director of the Albert Einstein College of Medicine, and Director of the Stern Stroke Center at Montefiore Medical Center. Dr. Rosenbaum earned his medical degree from Albert Einstein College of Medicine. He completed his internship at Brookdale Medical Center; his residency at Albert Einstein College of Medicine, where he was Chief Resident in the Department of Neurology; and a fellowship in cerebrovascular disease at University of Texas Medical School in Houston. Recognized as one of the Best Doctors in America®, Dr. Rosenbaum is listed in Consumers' Research Council of America: "Guide to America's Top Physicians" as well as Castle Connolly's "Best Doctors in the New York Metro Area." He has been honored with the Clinical Investigator Developmental Award by the National Institute of Neurological Disorders and Stroke and has published over 80 articles in all the major peer-reviewed journals. Dr. Rosenbaum is a member of the American Academy of Neurology, American Neurological Association, Society for Neuroscience, Stroke Council of the American Stroke Association, Association for Research in Vision and Ophthalmology and the International Society of Cerebral Blood Flow and Metabolism.

Editorial Board

  • Dongming Cai, MD, PhD

    Department of Neurology
    Icahn School of Medicine at Mount Sinai
    United States
    Dr. Cai joined Mount Sinai in 2010, where she works on understanding of the workings of the central nervous system and the processes involved in defining disease mechanisms. Prior to coming to Mount Sinai, Dr. Cai was trained by many prestigious basic research scientists. After graduated from Tongji Medical University in China, she obtained her PhD in Neuroscience in the laboratory of Dr. Marie Filbin at Hunter College of The City University of New York, where she studied the roles of cyclic AMP in blocking myelin-derived inhibitors of axonal regeneration in animal models of spinal cord injury. Subsequently, Dr. Cai completed postdoctoral training at Rockefeller University in New York where she was mentored by Nobel Laureate Dr. Paul Greengard in Laboratory of Molecular and Cellular Neuroscience. At Rockefeller University, Dr. Cai conducted research on Alzheimer’s disease focusing on the regulation of APP processing and trafficking and the impact of these processes on neuronal function. Besides her extensive basic research training, Dr. Cai obtained further clinical expertise in neurology and expanded her exposure to translational research during residency training at Yale’s Department of Neurology. She collaborated and continues to work with other research scientists in its Program in Cellular Neuroscience, Neurodegeneration and Repair at Yale to investigate the regulation of membrane lipid composition, metabolism and its effects on Alzheimer’s disease pathogenesis and progression.
  • James WY Chen, MD, PhD

    Director, WLAVA/UCLA Clinical Neurophysiology Fellowship Program; Associate Professor, Department of Neurology;
    University of California, Los Angeles
    United States
    Dr. James WY Chen had been comprehensively trained in the disciplines of both clinical and basic neurophysiology. His PhD training was in ion channel physiology of hair cells and sensory neurophysiology of the vestibular system. The research expertise includes using the patch clamp techniques to perform single channel and whole-cell recordings from potassium channels (KCN types, delayed rectifiers, inward rectifiers, IA,, Ik(Ca)), sodium channels and high-voltage activated calcium channels. During his research fellowship training after neurology residency, he had mastered the skills of in vivo intrinsic optical signal imaging and local field potential recordings including multi-unit recordings. On the clinical front, he is the board certified in Neurology, Epilepsy and Clinical Neurophysiology (with clinical expertise in EEG, evoked potentials, continuous video-EEG monitoring, electrocorticography, implanted intracranial electrode recording, cortical mapping with electrical stimulation, etc.). On the basic research front, his expertise involves hands-on recordings and data analysis of neurophysiological signals, bottom up from single ion channel recording, whole-cell recording, units and multi-units recordings, local field potentials, evoked potentials to EEG. He is familiar with several of the commonly used methods for quantitative data analysis, such as spectral analysis and independent component analysis. He had used these techniques in analyzing EEG and optical intrinsic signal imaging data. He had been on several leadership roles and has been successful in securing funding to initiate new fellowship training program in Clinical Neurophysiology and Epilepsy at WLAVA/UCLA. He had been the leading person to establish the new WLAVA Epilepsy Center of Excellence with comprehensive epilepsy cares (seizure clinic, telemedicine clinic, epilepsy monitoring units, phase II intracranial recording, cortical mapping, ECoG, resection surgery, vagus nerve stimulator implantation and programming, deep brain stimulator implantation and programming, introducing RNS treatment) since 2009. Currently, he is serving as the Program Director for the following programs: WLAVA/UCLA ACGME accredited Clinical Neurophysiology Fellowship program (2008-present), WLAVA Advanced Fellowship in Posttraumatic Epilepsy (2010-present), WLAVA/UCLA ACGME accredited Epilepsy Fellowship program (2015-) and the WLAVA Epilepsy Center of Excellence (2009-present). He also serves as the VA Southwestern Regional Director of the Epilepsy Centers of Excellence. He had been able to maintain and grow these programs significantly since the inception. The infrastructure of these clinical programs could be used to support conducting relevant research projects.
  • Bojun Chen, MD, PhD

    Assistant Professor, Department of Neuroscience
    University of Connecticut
    United States

    Dr. Chen received hid PhD in 2004 from Peking University, China, where he studied the function of MYB transcription factors in plants in the laboratory of Zhong-Ping Lin. He then moved to the United States and joined the laboratory of Zhao-Wen Wang at the University of Connecticut, where he worked as a postdoc and research associate studying the molecular mechanisms of synaptic transmission at the C. elegans neuromuscular junctions. Dr. Chen has worked as an Assistant Professor in the Department of Neuroscience at the University of Connecticut since 2013.

  • Bhuvaneswari Devi Chinthirla, PhD

    Department of Cell Biology and Neuroscience
    University of California, Riverside
    United States
    Dr. Chinthirla received her Ph.D degree from Sri Venkateswara University from India. She served as Assistant Professor in SVIMS University, India. Presently working in Dr. Margarita Curras Collazo’s lab in the department of Cell Biology and Neuroscience in the University of California, Riverside, CA, USA. She received Environmentalist Award from National Environmental Science Academy, New Delhi, India and Fast track woman scientist award from Department of Science and Technology, India. She is Life member for Association of Biotechnology and Pharmacy, Indian Society of Comparative Animal Physiology, National Environmental Science Academy.
  • Devin McBride, PhD

    Assistant Professor, Department of Neurosurgery
    University of Texas Health Science Center at Houston
    United States

    Dr. McBride received his Ph.D. in Bioengineering from the University of California, Riverside. His thesis work focused on the phenomenon of crowded protein osmotic pressure and its application to medical devices for treatment of severe brain swelling. During his Ph.D., Dr. McBride received several awards and fellowships, including a DOE GAANN Fellowship and a NSF IGERT Fellowship in Video Bioinformatics. He then spent four years as a post-doctoral fellow in Dr. John Zhang’s lab studying molecular mechanisms and therapeutic strategies of cerebrovascular disease (ischemic and hemorrhagic strokes). He was awarded a NIH Postdoctoral Fellowship to develop, understand, and treat vasovagal syncope. He is a member of AHA, National Neurotrauma Society, SFN, BMES, and AAAS.Dr. Dr. McBride currently works as an Assistant Professor in the Department of Neurosurgery at University of Texas Health Science Center at Houston.

  • Marykay A Pavol, PhD

    Assistant Professor, Stroke Division, Department of Neurology
    Columbia University
    United States

    Dr. Pavol is Assistant Professor of Clinical Neuropsychology in the Department of Neurology at the Columbia University College of Physicians & Surgeons at Columbia.She received her PhD in Clinical Neuropsychology from the University of Houston (Houston, TX) in 1995, completed an internship in Clinical Neuropsychology at University Hospital (London, Ontario, Canada) in 1995, and completed a fellowship in Rehabilitation Medicine at the Rehabilitation Institute of Michigan (Detroit, MI) in 1996. She has been board certified in Clinical Neuropsychology by the American Board of Professional Psychology since 1999. Dr. Pavol joined the Columbia University faculty in 2007 after many years in rehabilitation medicine settings. She has extensive experience in brain injury rehabilitation program coordination (inpatient and outpatient) as well as cognitive and neurobehavioral assessment with a range of medical diagnoses. She performs neuropsychological evaluations for inpatients and outpatients. In addition to her clinical responsibilities, Dr. Pavol’s research interests the relationship between cognition and carotid disease, cognition and heart failure (including left ventricular assistive devices), and cognition and rehabilitation medicine outcomes. She has coordinated training and certification in cognitive assessment for multiple research trials.

  • Qiangbin Wang, PhD

    Professor, Department of Nano-biomedicine
    Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences
    China (中国)

    Dr. Qiangbin Wang received his B.S. and Mater degrees in Chemistry from Petroleum University of China in 1996 and 1999, respectively. He got his Ph.D. in Material Sciences from East China University of Science and Technology in 2002, and then joined Shanghai Jiaotong University as a Research Associate. From 2004 to 2008, he worked as a Postdoctoral Associate and an Assistant Research Professor at Arizona State University. In July of 2008, he joined the faculty in Suzhou Institute of Nano-Tech and Nano-Bionics (SINANO), Chinese Academy of Sciences. He is currently Professor in the Division of Nano-biomedicine at SINANO. He is Distinguished Professor at Shanghai Tech University, and Guest Professor at University of Chinese Academy of Sciences.

  • Xiao-Ming Xu, PhD

    Professor, Department of Neurological Surgery
    Indiana University
    United States

    Dr. Xu received his Medical Diploma from Shanghai Second Medical University and Ph.D. in Anatomy/Neurobiology from The Ohio State University. He is currently the Mari Hulman George Professor of Neurological Surgery, and the Scientific Director of the Spinal Cord and Brain Injury Research Group at Indiana University School of Medicine. Dr. Xu’s research has focused on neuroprotection, and cell transplantation-mediated axonal regeneration and recovery of function following spinal cord injury. He has received continuous support from the National Institutes of Health (NIH), as well as support from the Department of Defense (DOD), Department of Veterans Affairs (VA) and Craig H Neilsen Foundation. He has served as a regular member on multiple NIH study sections. He has published over 150 research papers in prestige scientific journals such as Nature Neuroscience, Journal of Neuroscience, Annals of Neurology, Cerebral Cortex and Journal of Neurotrauma. He has co-edited books on “Animal Models of Acute Neurological Injuries” and on “Neural Regeneration”. He is the Editor-in-Chief of Neural Regeneration Research. He has also served as an editorial board member on several prestigious journals including Journal of Neurotrauma and Cell Transplantation. He is the Co-Chair of the International Neural Regeneration Symposiums (2011-2018).

  • Milton Biagioni, MD

    Assistant Professor, Department of Neurology
    New York University School of Medicine
    United States
    Dr. Biagioni received his medical degree from the National University of Rosario , Argentina; he completed a residency in Neurology in Juan A. Fernandez Hospital in Buenos Aires (Argentina) in 2009. In 2010 he was awarded the Blas Frangione Foundation Postdoctoral Research Award which supports postdoctoral research in neurodegenerative diseases. In particular, his main research focus was in biomarkers of Alzheimer’s disease and sleep disorders and mild cognitive impairment. In 2011, he started a Postdoctoral Research Fellowship in biomarkers of cognitive impairment in Parkinson's disease and neurophysiology research on motor control and motor learning at NYU Parkinson’s and Movement Disorder Center (NYUPMDC). In August 2014, Dr. Biagioni was appointed Assistant Professor at NYU Neurology Department and Associate Director of the transcranial magnetic stimulation (TMS) Laboratory at The Marlene and Paolo Fresco Institute for Parkinson’s and Movement Disorder.
  • Chin-Lung Kuo, MD, PhD

    Institute of Brain Science
    National Yang-Ming University
    Taiwan (台灣)

    Dr. Chin-Lung Kuo is the Director of the Department of Otolaryngology, Taoyuan Armed Forces General Hospital, Taiwan, ROC. Dr. Kuo received his medical degree from the National Defense Medical Center and earned his PhD degree at the Institute of Brain Science, National Yang-Ming University, Taiwan, ROC. He completed his otolaryngology residency, chief residency, and fellowship training at the Department of Otolaryngology-Head and Neck Surgery, Taipei Veterans General Hospital, Taiwan, ROC. Dr. Kuo continues to make contributions to the scientific community. His primary field of study is otology, and his research is focused on middle ear surgery and hearing loss. Dr. Kuo has been invited to speak at international conferences and institutes. Dr. Kuo has been the first or corresponding author on more than 50 published articles in the last 5 years, including SCI original papers, review articles, as well as book chapters. In 2012, his research paper was chosen as the cover story of the journal Audiology and Neurotology. In addition, Dr. Kuo received the Outstanding Paper Award from the Laser Medicine Education and Research Foundation in 2013, and was awarded the 2015 Hayashi SPIO (Society for Promotion of International Otorhinolaryngology) Scholarship in Japan. Dr. Kuo believes that increased availability of research data can benefit both medical research and science education. For further details regarding his research, please use the following link to access his blog.

  • Gary Kui Kai Lau, MBBS (HK), MRES (Med), MRCP (UK), FHKCP, FHKAM (Med)

    Clinical Assistant Professor, Division of Neurology, Department of Medicine
    University of Hong Kong
    China (中国)
    Dr. Gary Kui Kai Lau graduated in 2008 from the University of Hong Kong with a M.B.B.S and Master of Research in Cardiovascular Medicine degree. He obtained his M.R.C.P (UK) in 2011 and subsequently joined The Division of Neurology, University of Hong Kong as Clinical Assistant Professor in the same year as part of the University's Young Academic Scheme. He completed his Neurology residency at Queen Mary Hospital, Hong Kong in 2015 and was subsequently awarded an University of Oxford Croucher Scholarship in 2014 to further pursue post-graduate studies in stroke epidemiology at The University of Oxford, under the mentorship of Professor Peter Rothwell. Dr. Lau's main research interests include stroke epidemiology, small vessel disease and primary and secondary preventive strategies of stroke. His research work has been published in more than 30 international peer-reviewed journals including European Heart Journal, Neurology, Stroke, European Journal of Neurology, American Journal of Hypertension and Atherosclerosis.
  • Airong Li, MD, PhD

    Assistant Professor, Department of Neurology
    Harvard University
    United States
    Dr. Airong Li earned her PhD in medical genetics from University of Oxford and completed a post-doctoral training in genetics at Yale University School of Medicine. She is currently an Assistant Professor of Neurology at Harvard Medical School and Assistant Investigator at Massachusetts General Hospital. Dr. Li has studied genes associated with human diseases, including asthma, hypertension, ataxia telangiectasia, polycystic liver and kidney diseases and Alzheimer’s disease. Dr. Li is the co-author of more than 20 research publications in well-recognized journals including "Nature Genetics", "American Journal Human Genetics", "American Journal Medical Genetics" , "Human Molecular Genetics" , ‘PLOS ONE”, “Science Reports” etc. Dr. Li is the recipient of the NIH National Research Service Award, American Heart Association Scientist Development Award, Harvard Medical School Junior Faculty Award and Neuroscience Education and Research Foundation Award. Dr. Li’s current primary research interest is genetic studies of Alzheimer’s disease and hidradenitis suppurativa.
  • Ying Li, MD

    Professor, Department of Biomedical Sciences
    City University of Hong Kong
    China (中国)
    Dr. Li was educated in Beijing medical University (1962 – 1968). He was a general surgeon at the Qinghai, and oral-maxillofacial surgeon at Nanjing Medical School, China. He completed post-doctoral fellowship in department of internal medicine Hypertension, University Michigan, and then joined Gastroenterology at the University of Michigan, where he was appointed Assistant Research Scientist in 1997, and Research Professor in the University of Michigan Medical School Department of Internal Medicine in 2002. Professor Li joined Department Biomedical Science City University of Hong Kong in December 2009.
  • Ke Ning, MD, PhD

    Department of Neuroscience
    The University of Sheffield
    United Kingdom
    Dr. Ke Ning is a Senior Lecturer (Associate Professor) in Translational Neuroscience in the Department of Neuroscience at University of Sheffield, UK. His research focuses on gene therapy and stem cell research in neurodegenerative disorders (ALS, SMA, AD and PD). Dr Ning obtained his Bachelor's degree in medicine from First Military Medical University, Master's degree in neurosurgery from Sun Yatsen University of Medical Science and PhD degree in neuroscience from Third Military Medical University, China. He is specialized in viral-based gene therapy, stem cell biology, animal models and electrophysiology. He is also a Lecture Professor at Tongji University in China. He is the co-author of more than 20 research publications in well-recognized journals including "Nature Cell Biology", "Nature Neuroscience", "Nature Communications", "Science Translational Medicine", "PNAS" , "Human Molecular Genetics" , ‘EMBO J”, “Brain” , "The Journal of Neuroscience", etc. For further details regarding his research, please use the following link (http://sitran.org/people/ning/ and http://www.sheffield.ac.uk/neuroscience/staff/ning) to access his blog.
  • Monika Pawlik, PhD

    Center for Dementia Research
    The Nathan S.Kline Institute
    United States
    Dr. Pawlik specializes in Alzheimer’s disease and related neurodegenerative disorders, particularly early symptoms and potentially causal mechanisms. Her interest focuses on proteins involved in Alzheimer’s disease: the β Amyloid precursor protein (APP) more than tau proteins but also APP-like proteins (APLP1 and APLP2), Cystatin C which may be able to partially counteract APP through neurotrophic activity, Presenilin1, the catalytic subunit of the Gamma-secretase complex which cleaves APP to produce Abeta, Beta-secretases which cleave APP previous to the gamma-secretase, Autophagy related proteins such as LC3, Rabs and Atgs which are part of a mechanism initiated in early stages of Alzheimer’s disease and receptors interacting with APP or responding to APP (GABAergic, glutaminergic, noradrenergic, neurotrophic and Semaphorins) and their connected signaling cascades.
  • Najib Murr

    Department of Neurology
    Southern Illinois University
    United States

    Dr. Murr received his medical degree from the Lebanese University. He completed his residency training in neurology at the University of Nebraska Medical Center (UNKC) and Creighton University in Omaha Nebraska and fellowship in epilepsy/clinical neurophysiology at Vanderbilt University in Nashville TN. He held faculty position at the UNMC prior to joining SIU in 2014 as neurology residency program director. He is a reviewer for multiple medical journals including Canadian Journal of Neurological Sciences, American Family Physician, Journal of Neurological Sciences and others. He is a member of American Academy of Neurology and the American Epilepsy Society and serves on national committees.

  • Jang Yen Wu, PhD

    Professor, Department of Biomedical Science
    Florida Atlantic University
    United States
    Professor Jang Yen Wu completed his PhD in 1968 in Biochemistry at University of California, San Francisco Medical Center. He completed his post-doctoral training in 1970 in Biochemistry at University of California, Los Angeles. His research interests include neuroscience, neurotransmitters and neurological disorders. He has fellowships in Society for Neuroscience, American and International Society for Neurochemists and American Association for the Advancement of Science (AAAS). He is currently a professor in the Department of Biomedical Science at Florida Atlantic University. He is also the Chair in the Neuroscience Program Steering Committee at Florida Atlantic University.

Assistant Editors

    Coming Soon...

Early View

  • Tourniquet-Induced Sciatic Nerve Injury: An Unusual Complication of Coronary Artery Bypass Graft Surgery

    A 53-year-old man with hypertension underwent CABG. Following surgery, he developed left leg numbness and weakness. Examination revealed left sciatic neuropathy, as well as a circumferential lesion over the left mid-thigh which was revealed to be due to a surgical tourniquet. He was diagnosed with tourniquet-induced left sciatic neuropathy, and by the end of his hospitalization, recovered full strength and sensation in his left lower extremity.

    Neurology and Neuroscience Research. 2018;2(1):1
    DOI: 10.24983/scitemed.nnr.2018.00074
    Article Type: Case Report

Current Issue

Volume 1, Issue 1

  • Neuroplasticity-targeted Intervention for Idiopathic Sudden Sensorineural Hearing Loss: A New Therapeutic Direction

    This current review addresses the topic of therapeutic strategies for idiopathic SSNHL from the perspective of neuroplasticity. Assertions pertaining to the plausibility of this approach are based on a large body of evidence from animal experiments and recent studies on humans.

    Neurology and Neuroscience Research. 2017;1(1):1
    DOI: 10.24983/scitemed.nnr.2017.00014
    Article Type: Review Article
  • The Chain of Chirality Transfer as Determinant of Brain Functional Laterality

    The authors briefly summarize advances in the broad field of biochirality connecting two poles of the phenomena: the atomic orbitals and the brain’s cognitive function. Analysis of current results allows introducing the new generation of entangled biomarkers ranging from the molecular chirality to laterality of cognitive and executive functions.

    Neurology and Neuroscience Research. 2017;1(1):2
    DOI: 10.24983/scitemed.nnr.2017.00028
    Article Type: Review Article
  • Over Effective Control of Glycemic Levels Could Cause Cognitive Decline in Diabetic Geriatric Population

    Diabetes control in the studied population could be too strict, and consequently, hypoglycemia in these patients could play a role in the major decline of cognitive function. Therefore, avoiding treatments that could lead to hypoglycemia in these patients could be very important. The aim of the treatment of diabetes in elderly patients is focused on stabilization, prevention of acute complications, and improving the quality of life.

    Neurology and Neuroscience Research. 2017;1(1):3
    DOI: 10.24983/scitemed.nnr.2017.00047
    Article Type: Original Article
  • Could the Brain Function Mathematically?

    Authors have put forth a hypothesis that the brain bears the innate capability of performing high-level mathematical computing in order to perform certain cognitive tasks. Authors give examples of Orthogonalization and Fourier transformation and argue that the former may correspond to the physiological action the brain performs to compare incoming information and put them in categories, while the latter could be responsible for the holographic nature of the long-term memory, which is known to withstand trauma. Authors plead that this proposal may not be as strange as it may appear, and argue how this line of mathematical modeling can have far-reaching consequences.

    Neurology and Neuroscience Research. 2018;1(1):4
    DOI: 10.24983/scitemed.nnr.2018.00064
    Article Type: Idea and Innovation
  • Spinal Cord Compression Due to a Catheter Tip Granuloma of an Intrathecal Morphine Pump

    Spinal cord compression due to a catheter tip granuloma of an intrathecal morphine pump.

    Neurology and Neuroscience Research. 2018;1(1):5
    DOI: 10.24983/scitemed.nnr.2018.00066
    Article Type: Image

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