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Mucocele of the Blandin-Nuhn Glands

Archives of Otorhinolaryngology-Head & Neck Surgery. 2017;1(1):3
DOI: 10.24983/scitemed.aohns.2017.00011
Article Type: Image

Abstract

Keywords

    A 31-year-old man was presented for assessment of a mass in the midline of the ventral surface of the anterior tongue. The size of the lesion had varied since it was first noticed 3 months ago. According to his medical history, the onset of the mass was associated with trauma to the anterior tongue in a car accident. Examination of the tongue revealed a nontender, fluctuant, bluish mass of approximately 8 mm in diameter (Panel A-C). It was diagnosed that the mass was a mucocele derived from the glands of Blandin and Nuhn. We performed complete surgical excision of the mass (Panel D) and no recurrence had been detected during one year of follow-up.
     

    Figure 1. Mucocele of the Blandin-Nuhn glands


    The glands of Blandin and Nuhn are mainly mucus-secreting glands that are embedded within the muscle tissues of the anterior tongue ventrum [1]. The cystic formation of the Blandin-Nuhn glands on the ventral surface of the tongue is usually exophytic and may resemble diseases like pyogenic granulomata, polyps, or squamous papillomata [1]. The disease is an uncommon benign lesion, which is rarely found in adults [2]. Most of the cases reported in the medical literature were females [1]. The localization of lesion, a trauma history, rapid onset, variation in size, bluish color and fluid-filled consistency are helpful clues in the diagnosis of a mucocele derived from the glands of Blandin and Nuhn. Complete extirpation of the mucocele may be guaranteed by performing surgical excision of the lesion along with the associated glandular components to avoid recurrences. This is because the Blandin-Nuhn glands are not encapsulated, but are embedded to the musculature of the anterior tongue ventrum [3].

    References

    1. Andiran N, Sarikayalar F, Unal OF, Baydar DE, Ozaydin E. Mucocele of the anterior lingual salivary glands: from extravasation to an alarming mass with a benign course. International journal of pediatric otorhinolaryngology 2001;61:143-147. PMID: 11589981
    2. Lypka M, Hammoudeh J. Images in clinical medicine. Tongue mucocele. The New England journal of medicine 2011;365:e9. PMID: 21793741; DOI: 10.1056/NEJMicm1013092
    3. Adachi P, Soubhia AM, Horikawa FK, Shinohara EH. Mucocele of the glands of Blandin-Nuhn--clinical, pathological, and therapeutical aspects. Oral and maxillofacial surgery 2011;15:11-13. PMID: 20393765; DOI: 10.1007/s10006-010-0221-1

    Editorial Information

    Publication History

    Received date: May 01, 2017
    Accepted date: May 14, 2017
    Published date: May 14, 2017

    Copyright

    © 2017 The Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International License (CC-BY).

    Department of Otolaryngology-Head and Neck Surgery, Taoyuan Armed Forces General Hospital, Taoyuan, Taiwan
    Department of Otolaryngology-Head and Neck Surgery, Taoyuan Armed Forces General Hospital, Taoyuan, Taiwan
    Email: drkuochinlung@gmail.com

    Reviewer’s Comments
     

    1. Mucocele in the oral cavity is usually associated with repetitive cheek biting or lip biting. Did the patient have any trauma history of the tongue?
      ResponseThe medical history of the patient revealed that the onset of the mass was associated with trauma to the anterior tongue in a car accident, which indicates that trauma may signify an initiating factor.
       
    1. A fine needle aspiration may be helpful in the clinical diagnosis of mucocele of the glands of Blandin and Nuhn. Did the patient undergo a fine needle aspiration prior to surgery?
      ResponseNo, we did not perform a fine needle aspiration prior to surgery. However, the localization of lesion, a trauma history, rapid onset, variation in size, bluish color and fluid-filled consistency are helpful clues in the diagnosis of a mucocele of the glands of Blandin and Nuhn.
       
    1. Is the treatment of mucocele of the glands of Blandin and Nuhn different from those of the other oral mucoceles?
      ResponseSince the Blandin-Nuhn glands are not encapsulated, but are embedded to the musculature of the anterior tongue ventrum, their treatment is likely to be different from the other oral mucoceles. Complete extirpation of the mucocele may be guaranteed by performing surgical excision of the lesion along with the associated glandular components to avoid recurrences.