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Looking Beyond the Obvious! A Case of Sialolithiasis Masquerading as an Odontogenic Abscess

Archives of Otorhinolaryngology-Head & Neck Surgery. 2023;7(1):2
DOI: 10.24983/scitemed.aohns.2023.00170
Article Type: Image

Abstract

Keywords

  • Abscess; ear; facial pain; gland; infections; salivary gland calculi; tooth

A 33-year-old female with an unremarkable medical history presented to the clinic with concerns about the acute onset of right-sided facial swelling accompanied by severe pain, dysphonia, and dysphagia. The patient reported a history of chronic pain associated with the lower right first molar. She had received a root canal treatment on the same tooth one month prior to presentation. On the night before her visit, she noticed facial swelling that rapidly progressed overnight and was accompanied by severe pain radiating to her right ear, which prompted her to seek medical evaluation. Furthermore, the patient noted new-onset difficulties swallowing solids and liquids, as well as speaking full sentences. Further evaluation and diagnostic imaging were ordered to investigate the cause of these symptoms.

The patient exhibited stable vital signs during examination. The presentation included facial swelling overlying the inferior border of the mandible, extending from the ramus anteriorly to the body of the mandible. On examination, the patient displayed a satisfactory level of mouth opening. Intra-oral examination revealed a raised floor of the mouth, which was tender upon palpation, along with fluctuation and induration. The patient's voice was strained and soft. Panoramic imaging showed a radiolucency associated with the previously treated tooth (Panel A), indicating an odontogenic abscess in the setting of failed root canal treatment. These clinical and radiographic findings prompted further evaluation and treatment, and the patient was referred to the emergency department for additional work-up and intravenous antibiotics.

At the emergency department, a flexible fiberoptic nasopharyngolaryngoscopy was performed at the bedside by an otolaryngologist. The examination revealed a patent airway without any notable findings. Subsequently, neck computed tomography imaging with contrast was carried out, which demonstrated radio-opacities along the right submandibular duct's course. Accompanying fat stranding was observed overlying the right mandible, without any indication of fluid collections (Panel B). Based on these results, sialolithiasis was deduced to be the most plausible diagnosis. Upon discharge, the patient was prescribed a course of antibiotics containing Amoxicillin-potassium clavulanate (Augmentin), sialagogues, and warm compresses. Following a two-week follow-up, the patient claimed near-total recovery after the passage of a salivary stone.

Upon initial evaluation, concerns were raised about a rapidly advancing odontogenic abscess that had the potential to invade the submandibular and neck spaces, posing a risk to the airway. Consequently, immediate or emergent care was deemed necessary, including incision and drainage, as well as odontectomy for source control. However, this case demonstrated that sialolithiasis may present in a similar fashion due to its proximity to adjacent structures. Therefore, the clinical presentation may resemble that of an odontogenic abscess. This case underscores the importance of keeping anatomic structures in mind when establishing a differential diagnosis. It also emphasizes the significance of avoiding tunnel vision when looking for the likely cause of clinical presentation.

Editorial Information

Publication History

Received date: February 26, 2023
Accepted date: March 02, 2023
Published date: March 08, 2023

Disclosure

The manuscript has not been presented or discussed at any scientific meetings, conferences, or seminars related to the topic of the research.

Ethics Approval and Consent to Participate

The study adheres to the ethical principles outlined in the 1964 Helsinki Declaration and its subsequent revisions, or other equivalent ethical standards that may be applicable. These ethical standards govern the use of human subjects in research and ensure that the study is conducted in an ethical and responsible manner. The researchers have taken extensive care to ensure that the study complies with all ethical standards and guidelines to protect the well-being and privacy of the participants.

Funding

The author(s) of this research wish to declare that the study was conducted without the support of any specific grant from any funding agency in the public, commercial, or not-for-profit sectors. The author(s) conducted the study solely with their own resources, without any external financial assistance. The lack of financial support from external sources does not in any way impact the integrity or quality of the research presented in this article. The author(s) have ensured that the study was conducted according to the highest ethical and scientific standards.

Conflict of Interest

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Copyright

© 2023 The Author(s). The article presented here is openly accessible under the terms of the Creative Commons Attribution 4.0 International License (CC-BY). This license grants the right for the material to be used, distributed, and reproduced in any way by anyone, provided that the original author(s), copyright holder(s), and the journal of publication are properly credited and cited as the source of the material. We follow accepted academic practices to ensure that proper credit is given to the original authors and the copyright holder(s), and that the original publication in this journal is cited accurately. Any use, distribution, or reproduction of the material must be consistent with the terms and conditions of the CC-BY license, and must not be compiled, distributed, or reproduced in a manner that is inconsistent with these terms and conditions. We encourage the use and dissemination of this material in a manner that respects and acknowledges the intellectual property rights of the original author(s) and copyright holder(s), and the importance of proper citation and attribution in academic publishing.

Department of Oral and Maxillofacial Surgery, Henry M. Goldman School of Dental Medicine, Boston University, Boston, MA, USA
Department of Oral and Maxillofacial Surgery, Henry M. Goldman School of Dental Medicine, Boston University, Boston, MA, USA
Department of Oral and Maxillofacial Surgery, Henry M. Goldman School of Dental Medicine, Boston University, Boston, MA, USA
Email: kiang.kev@gmail.com
Address: 635 Albany St, Boston, MA 02118, USA
Figure.JPG
Figure Radiographic evidence of radiolucency corresponding to prior root canal therapy is noted in the panoramic image (Panel A), indicative of an odontogenic abscess resulting from an unsuccessful treatment. However, contrast-enhanced computed tomography of the neck reveals radio-opacities along the right submandibular duct (Panel B), with accompanying fat stranding overlying the right mandible and no evidence of fluid collections. These findings support the diagnosis of sialolithiasis as the most plausible explanation.

Round 1

Reviewer 1 Comments

  1. The presented case study involves a 33-year-old female who experienced severe pain, facial swelling, dysphonia, and dysphagia after root canal treatment of a mandibular molar. The study possesses noteworthy features, rendering it deserving of publication. Firstly, it highlights a rare, yet potentially lethal condition that may be erroneously diagnosed if not managed with appropriate clinical proficiency. Secondly, it underscores the importance of considering an extensive range of differential diagnoses when evaluating patients with comparable manifestations. Lastly, it accentuates the crucial role of adequate imaging techniques in enabling clinicians to establish accurate diagnoses and promptly administer interventions. Publication of this case report can provide valuable insights to clinicians, researchers, and students alike, potentially enhancing patient outcomes. However, some minor issues may need to be addressed before acceptance for publication.
    ResponseThank you for your interest in our case report. We are delighted that this case can be of value to our community of clinicians, researchers, and students. We were unsure with how much detail to put into the initial submission; however it would seem that I was too sparse with details of this patient encounter and I have gladly revised the submission in greater detail under the guidance of your comments! Below, each comment is addressed point-by-point. In the revision, in bolded parenthesis are the sections of the text which have been revised in response to your comments. I hope this provides a clear clinical picture of the timeline of the patient’s history.
     
  2. The medical condition under consideration lacks clarity as key details are missing from the case report. It is imperative to establish whether the patient has any relevant past medical history that could be associated with the onset of the disease.
    ResponseThe patient denies any past medical history and surgical history, including a history of salivary stones.
     
  3. It was determined that the final diagnosis was sialolithiasis-related complications, but the period of time between the root canal treatment on the mandibular molar and the development of the symptoms and signs must be determined in order to rationalize the original suspicion of an odontogenic abscess.
    ResponseThis patient reports she had chronic dental pain for which she underwent root canal treatment roughly 1 month prior to presentation to our clinic.
     
  4. A clear description of the duration of symptoms, which include severe acute onset pain, right facial swelling, dysphonia, and dysphagia, would also be beneficial.
    ResponseThe duration of her symptoms were quite acute and rapid, developing the night before she presented to our clinic. We have added in detail the character and evolution of her symptoms as well as more detailed exam findings.

Reviewer 2 Comments

  1. The present article documents a case in which a 33-year-old female patient experienced considerable discomfort, facial swelling, and difficulty with speech and swallowing following a root canal procedure on her mandibular molar. Physical examination revealed an elevated floor of the mouth, and imaging studies identified a radiolucency in the affected tooth. Subsequent CT scans revealed radio-opacities in the submandibular duct path. While the initial suspicion was of an odontogenic abscess, the ultimate diagnosis was sialolithiasis, as the condition was found to be in close proximity to neighboring structures. The patient was treated with antibiotics, sialagogues, and warm compresses, and her condition improved significantly. The case underscores the importance of considering anatomical structures while formulating differential diagnoses and avoiding overreliance on narrow diagnostic assumptions. Despite the clinical significance of the presented case study, certain limitations exist that may impede its suitability for publication in its current state.
    ResponseThank you for your interest in our case report. We are delighted that this case can be of value to our community of clinicians, researchers, and students. We were unsure with how much detail to put into the initial submission, however it would seem that I was too sparse with details of this patient encounter and I have gladly revised the submission in greater detail under the guidance of your comments! Below, each comment is addressed point-by-point. In the revision, in bolded parenthesis are the sections of the text which have been revised in response to your comments. I hope this provides a clear clinical picture of the timeline of the patient’s history.
     
  2. The initial differential diagnosis involved an odontogenic abscess that was rapidly progressing and posing a risk to the patient's airway, potentially involving both the mandibular and neck spaces. The patient's past history of root canal treatment may have contributed to this condition, although the exact temporal relationship between the two events remains unclear. This ambiguity in the timeline could diminish the article's relevance and applicability to other medical professionals. An in-depth understanding of the case can be achieved by presenting the medical history in chronological order, specifying the exact time period. There is a need for further clarification on this point.
    ResponseWe have clarified the timeline of the dental treatment and the evolution of the patient’s symptoms. We hope this clarifies the concern for an odontogenic abscess in initial exam given chronic dental pain with a root canal treatment in the past month in which a root canal treated tooth could be complicated by development of an abscess due to failure of the treatment itself.
     
  3. Dysphonia and dysphagia were symptoms that the patient presented with at the clinic. A neck CT (Panel B) revealed a deviation of the airway in the neck. Before releasing the patient to her home, did the emergency room physician examine the patient with a fiberscope to determine whether her airway was completely intact?
    ResponseWe’re glad you asked! Yes, an otolaryngology consult was placed for an airway evaluation and a fiberoptic exam was conducted to evaluate the airway given concern for airway as well as new and acute changes to the patient’s voice.  We have included this detail in our revision.

Editorial Comments

  1. An informative, concise title would enhance the effectiveness of this article while preserving its impressive quality. An example would be: Looking Beyond the Obvious! A Case of Sialolithiasis Masquerading as an Odontogenic Abscess.
    ResponseDear editor, thank you for your comment – We quite enjoyed the title you have provided as an example and have changed our title to that!
     

Round 2

Editor’s Comments

The patient was a 33-year-old female who presented with sudden onset facial swelling, pain, dysphonia, and dysphagia. Upon physical examination, swelling over the inferior mandibular border was observed, and panoramic imaging revealed radiolucency associated with a recently treated tooth, indicating an odontogenic abscess. A CT scan showed radio-opacities along the right submandibular duct, fat stranding over the right mandible, and an absence of fluid collections, consistent with sialolithiasis. The patient was treated with antibiotics, sialagogues, and warm compresses, and subsequently recovered after the discharge of a salivary stone. This case highlights the rare incident of sialolithiasis masquerading as an odontogenic abscess. It underlines the need for an exhaustive history, physical assessment, and radiographic examination to ensure a precise diagnosis and treatment. The manuscript has been exhaustively revised and complies with academic publication standards.

Kiang K, Sethi A. Looking beyond the obvious! A case of sialolithiasis masquerading as an odontogenic abscess. Arch Otorhinolaryngol Head Neck Surg. 2023;7(1):2. https://doi.org/10.24983/scitemed.aohns.2023.00170